Construction Vehicles/18-Wheelers - Heavy Traffic on Edwards St

Is there anything we can do about the constant use of Edwards Street by large construction vehicles and 18-wheelers? They seemingly drive by regularly at all hours of the day and night, especially in the early morning. They create a lot of noise just driving, and oftentimes they even honk (I'm thinking this must be at the protestors that are regularly at Planned Parenthood on Edwards & Whitney). There are frequently dump trucks that use Edwards St, I think to get to the construction that is happening on Yale's Science Hill. Edwards St seems to be overwhelmingly residential as far as I can tell, and as a result I think should not be used this heavily by construction or commercial vehicles.